Selected publications from the ART Lab are listed below.

2025

Nunez, C., Yoon, J. H., de Dios, C., Dang, V., Lane, S. D., Vincent, J. N., Schmitz, J. M., & Wardle, M. C. (2025). Undervaluing nondrug rewards or overvaluing cocaine? Cocaine demand relates to cocaine use severity more strongly than anhedonia in individuals with cocaine use disorder. Experimental and clinical psychopharmacology, 33(1), 91–99. https://doi.org/10.1037/pha0000744

Hull, K., Bing-Canar, H., Miloslavich, K., Holden, C., Ahluwalia, A., Lane, S. D., Schmitz, J. M., & Wardle, M. C. (2025). Exploring the Role of Reward Functioning in the Overlap of Post-Traumatic Stress and Cocaine Use Disorder. Substance use & misuse, 60(6), 926–932. https://doi.org/10.1080/10826084.2025.2465983

2024

Wardle, M. C., Webber, H. E., Yoon, J. H., Heads, A. M., Stotts, A. L., Lane, S. D., & Schmitz, J. M. (2024). Behavioral therapies targeting reward mechanisms in substance use disorders. Pharmacology, biochemistry, and behavior, 240, 173787. https://doi.org/10.1016/j.pbb.2024.173787

Miloslavich, K., & Wardle, M. (2024). Anger is more strongly associated with alcohol and tobacco use and use disorders compared to other substances in American adults. The American journal of drug and alcohol abuse, 50(4), 433–441. https://doi.org/10.1080/00952990.2024.2331721

2023

Wardle, M. C., Hoots, J. K., Miloslavich, K., Nunez, C., Dios, C., Holden, C., Ahluwahlia, A., Green, C. E., Lane, S. D., & Schmitz, J. M. (2023). Deficits in consummatory reward relate to severity of cocaine use. Drug and alcohol dependence, 249, 109950. https://doi.org/10.1016/j.drugalcdep.2023.109950

Hamidovic, A., Davis, J., Wardle, M., Naveed, A., & Soumare, F. (2023). Periovulatory Subphase of the Menstrual Cycle Is Marked by a Significant Decrease in Heart Rate Variability. Biology, 12(6), 785. https://doi.org/10.3390/biology12060785

Suchting, R., Razouq, D., Jose, L., Nascimento E Silva, F., Wardle, M. C., Soares, J. C., Teixeira, A. L., & Selvaraj, S. (2023). Effects of an experimentally induced inflammatory stimulus on motivational behavior in remitted depressed patients. Journal of psychiatric research, 161, 106–111. https://doi.org/10.1016/j.jpsychires.2023.03.019

Miloslavich, K., Leonard, S. J., Wardle, M. C., & Vujanovic, A. A. (2023). Alcohol Use Severity, Anger and Drinking Motives among Firefighters. Substance use & misuse, 58(5), 601–609. https://doi.org/10.1080/10826084.2023.2177113

Hamidovic, A., Davis, J., Soumare, F., Naveed, A., Ghani, Y., Semiz, S., Khalil, D., & Wardle, M. (2023). Allopregnanolone Is Associated with a Stress-Induced Reduction of Heart Rate Variability in Premenstrual Dysphoric Disorder. Journal of clinical medicine, 12(4), 1553. https://doi.org/10.3390/jcm12041553

Webber, H. E., Yoon, J. H., de Dios, C., Suchting, R., Dang, V., Versace, F., Green, C. E., Wardle, M. C., Lane, S. D., & Schmitz, J. M. (2023). Assessing cocaine motivational value: Comparison of brain reactivity bias toward cocaine cues and cocaine demand. Experimental and clinical psychopharmacology, 31(4), 861–867. https://doi.org/10.1037/pha0000622

Nunez, C., Hoots, J. K., Schepers, S. T., Bower, M., de Wit, H., & Wardle, M. C. (2022). Pharmacological investigations of effort-based decision-making in humans: Naltrexone and nicotine. PloS one, 17(10), e0275027. https://doi.org/10.1371/journal.pone.0275027

Zegel, M., McGrew, S. J., Wardle, M. C., & Vujanovic, A. A. (2023). The main and interactive effects of distress tolerance and reward function on posttraumatic stress disorder symptoms among firefighters. Psychological Trauma: Theory, Research, Practice, and Policy, 15(Suppl 2). https://doi.org/10.1037/tra0001240

Wardle, M., Hoots, J., Miloslavich, K., Nunez, C., Holden, C., Ahluwalia, A., Lane, S., & Schmitz, J. (2023). Domains of reward functioning in cocaine use disorder. Biological Psychiatry, 93(9). https://doi.org/10.1016/j.biopsych.2023.02.125

Webber, H. E., Yoon, J. H., de Dios, C., Suchting, R., Dang, V., Versace, F., Green, C. E., Wardle, M. C., Lane, S. D., & Schmitz, J. M. (2023). Assessing cocaine motivational value: Comparison of brain reactivity bias toward cocaine cues and cocaine demand. Experimental and Clinical Psychopharmacology, 31(4), 861–867. https://doi.org/10.1037/pha0000622

2022

Webber, H. E., Yoon, J. H., de Dios, C., Suchting, R., Dang, V., Versace, F., Green, C. E., Wardle, M. C., Lane, S. D., & Schmitz, J. M. (2022). Assessing cocaine motivational value: Comparison of brain reactivity bias toward cocaine cues and cocaine demand. Experimental and clinical psychopharmacology, 10.1037/pha0000622. Advance online publication. https://doi.org/10.1037/pha0000622

Nunez, C., Hoots, J. K., Schepers, S. T., Bower, M., de Wit, H., & Wardle, M. C. (2022). Pharmacological investigations of effort-based decision-making in humans: Naltrexone and nicotine. PloS one, 17(10), e0275027. https://doi.org/10.1371/journal.pone.0275027

Wardle, M. C., Pabon, E., Webber, H. E., & de Wit, H. (2022). Delta-9-tetrahydrocannabinol reduces willingness to exert effort in women. Psychopharmacology, 239(5), 1487–1497. https://doi.org/10.1007/s00213-021-06032-1

2021

Hoots, J. K., Webber, H. E., Nunez, C., Cooper, J. A., Lopez-Gamundi, P., Lawlor, V. M., Lane, S. D., Treadway, M. T., & Wardle, M. C. (2021). Acute drug effects differentially predict desire to take dextroamphetamine again for work and recreation. Psychopharmacology, 238(10), 2815–2826. https://doi.org/10.1007/s00213-021-05897-6

Webber, H.E., Lopez-Gamundi, P., Stamatovich, S.N., de Wit, H., & Wardle, M.C. (2021). Using pharmacological manipulations to study the role of dopamine in human reward functioning: A review of studies in healthy adults. Neuroscience and biobehavioral reviews, 120, 123–158. https://doi.org/10.1016/j.neubiorev.2020.11.004

Stamatovich, S.N., Lopez-Gamundi, P., Suchting, R., Colpo, G.D., Walss-Bass, C., Lane, S.D., Schmitz, J.M., & Wardle, M.C. (2021). Plasma pro- and anti-inflammatory cytokines may relate to cocaine use, cognitive functioning, and depressive symptoms in cocaine use disorder. The American journal of drug and alcohol abuse, 47(1), 52–64. https://doi.org/10.1080/00952990.2020.1828439

Soder, H.E., Cooper, J.A., Lopez-Gamundi, P., Hoots, J.K., Nunez, C., Lawlor, V.M., Lane, S.D., Treadway, M.T., & Wardle, M.C. (2021). Dose-response effects of d-amphetamine on effort-based decision-making and reinforcement learning. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 46(6), 1078–1085. https://doi.org/10.1038/s41386-020-0779-8

2020

Agurto, C., Cecchi, G.A., Norel, R., Ostrand, R., Kirkpatrick, M., Baggott, M.J., Wardle, M.C., Wit, H., & Bedi, G. (2020). Detection of acute 3,4-methylenedioxymethamphetamine (MDMA) effects across protocols using automated natural language processing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 45(5), 823–832. https://doi.org/10.1038/s41386-020-0620-4

Soder, H.E., Berumen, A.M., Gomez, K.E., Green, C.E., Suchting, R., Wardle, M.C., … Lane, S.D. (2020). Elevated Neutrophil to Lymphocyte Ratio in Older Adults with Cocaine Use Disorder as a Marker of Chronic Inflammation. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 18(1), 32–40. https://doi.org/10.9758/cpn.2020.18.1.32

Addicott, M.A., Wardle, M.C., & Selig, J.P. (2020). Effort-based decision making varies by smoking status. Psychopharmacology, 10.1007/s00213-019-05437-3. Advance online publication. https://doi.org/10.1007/s00213-019-05437-3

2019

Soder, H.E., Wardle, M.C., Schmitz, J.M., Lane, S.D., Green, C., & Vujanovic, A.A. (2019). Baseline resting heart rate variability predicts post-traumatic stress disorder treatment outcomes in adults with co-occurring substance use disorders and post-traumatic stress. Psychophysiology, 56(8), e13377. https://doi.org/10.1111/psyp.13377

Suchting, R., Vincent, J.N., Lane, S.D., Green, C.E., Schmitz, J.M., & Wardle, M.C. (2019). Using a data science approach to predict cocaine use frequency from depressive symptoms. Drug and alcohol dependence, 194, 310–317. https://doi.org/10.1016/j.drugalcdep.2018.10.029

Fries, G.R., Khan, S., Stamatovich, S., Dyukova, E., Walss-Bass, C., Lane, S.D., … Wardle, M.C. (2018). Anhedonia in cocaine use disorder is associated with inflammatory gene expression. PloS one, 13(11), e0207231. https://doi.org/10.1371/journal.pone.0207231

2018

Wardle, M.C., Lopez-Gamundi, P., & LaVoy, E.C. (2018). Effects of an acute bout of physical exercise on reward functioning in healthy adults. Physiology & behavior, 194, 552–559. https://doi.org/10.1016/j.physbeh.2018.07.010

Vujanovic, A.A., Wardle, M.C., Bakhshaie, J., Smith, L.J., Green, C.E., Lane, S.D., & Schmitz, J.M. (2018). Distress tolerance: Associations with trauma and substance cue reactivity in low-income, inner-city adults with substance use disorders and posttraumatic stress. Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 32(3), 264–276. https://doi.org/10.1037/adb0000362

Lopez-Gamundi, P., & Wardle, M.C. (2018). The cognitive effort expenditure for rewards task (C-EEfRT): A novel measure of willingness to expend cognitive effort. Psychological assessment, 30(9), 1237–1248. https://doi.org/10.1037/pas0000563

Wardle, M.C., Lopez-Gamundi, P., & Flagel, S.B. (2018). Measuring appetitive conditioned responses in humans. Physiology & behavior, 188, 140–150. https://doi.org/10.1016/j.physbeh.2018.02.004

2017

Vujanovic, A.A., Wardle, M.C., Smith, L.J., & Berenz, E.C. (2017). Reward functioning in posttraumatic stress and substance use disorders. Current opinion in psychology, 14, 49–55. https://doi.org/10.1016/j.copsyc.2016.11.004

Wardle, M.C., Vincent, J.N., Suchting, R., Green, C.E., Lane, S.D., & Schmitz, J.M. (2017). Anhedonia Is Associated with Poorer Outcomes in Contingency Management for Cocaine Use Disorder. Journal of substance abuse treatment, 72, 32–39. https://doi.org/10.1016/j.jsat.2016.08.020